Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Secure web book to store structural genomics research data.

Babu A Manjasetty1, Klaus Höppner, Uwe Mueller

  • 1Protein Structure Factory, c/o BESSY GmbH, Albert-Einstein Str.15, 12489, Berlin, Germany.

Journal of Structural and Functional Genomics
|December 3, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Structure-guided identification and characterization of a novel pyrazolo[1,5-a]pyrimidine ligand of SARS-CoV-2 main protease.

International journal of biological macromolecules·2026
Same author

Wolfram Saenger (1939-2026).

Structure (London, England : 1993)·2026
Same author

Wolfram Saenger (1939-2026).

Acta crystallographica. Section D, Structural biology·2026
Same author

Enhancing the Outcome of Crystallographic Fragment Screening by Choosing the Optimal Protein Crystal Form.

Small science·2026
Same author

Erratum: A simple goniometer-compatible flow cell for serial synchrotron X-ray crystallography. Corrigendum.

Journal of applied crystallography·2025
Same author

From fragments to follow-ups: rapid hit expansion by making use of EU-OPENSCREEN resources.

RSC medicinal chemistry·2025
Same journal

Protein sequence-similarity search acceleration using a heuristic algorithm with a sensitive matrix.

Journal of structural and functional genomics·2017
Same journal

Toward the next step in G protein-coupled receptor research: a knowledge-driven analysis for the next potential targets in drug discovery.

Journal of structural and functional genomics·2017
Same journal

Special issue: big data analyses in structural and functional genomics.

Journal of structural and functional genomics·2017
Same journal

Classification of ligand molecules in PDB with graph match-based structural superposition.

Journal of structural and functional genomics·2016
Same journal

VaProS: a database-integration approach for protein/genome information retrieval.

Journal of structural and functional genomics·2016
Same journal

NLDB: a database for 3D protein-ligand interactions in enzymatic reactions.

Journal of structural and functional genomics·2016
See all related articles

A new web-based system, BCLIMS, streamlines protein structure analysis by managing synchrotron X-ray diffraction data. This information management system enhances collaboration in structural genomics projects.

Area of Science:

  • Structural biology
  • Bioinformatics
  • Computational chemistry

Background:

  • Collaborative structural genomics programs accelerate protein crystal structure determination.
  • Efficient data management is crucial for large-scale, multi-group scientific endeavors.
  • The Protein Structure Factory in Berlin utilizes BESSY synchrotron for X-ray data collection and structure analysis.

Purpose of the Study:

  • To develop a system for organizing file-based communication and data transfer at the BESSY synchrotron site.
  • To introduce the BESSY Crystallography Laboratory Information Management System (BCLIMS) for managing laboratory information.
  • To describe the storage, retrieval, and manipulation of data related to synchrotron X-ray diffraction experiments and protein structure analysis.

Main Methods:

Related Experiment Videos

  • Development of a web-based Laboratory Information Management System (LIMS) named BCLIMS.
  • Implementation of a relational database using MySQL.
  • Utilization of the Apache HTTP web server for the system.
  • Database interface routines written in Python programming language.

Main Results:

  • BCLIMS provides a centralized platform for managing protein structure analysis data.
  • The system facilitates efficient storage, retrieval, and manipulation of experimental and analytical information.
  • The software is freely available for academic users, promoting wider adoption.

Conclusions:

  • BCLIMS effectively addresses the data management needs of collaborative structural genomics projects.
  • The system enhances workflow efficiency for synchrotron X-ray diffraction experiments and protein structure determination.
  • BCLIMS supports seamless collaboration among scientists by organizing critical laboratory information.