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Pituitary oncocytoma: three cases report.

C J Wang¹, S L Howng, F F Sun

¹Department of Surgery, Kaohsiung Medical College, Taiwan, Republic of China.

Gaoxiong Yi Xue Ke Xue Za Zhi = the Kaohsiung Journal of Medical Sciences

|August 1, 1992

Summary

Pituitary oncocytomas are rare tumors. Surgical removal (transsphenoidal adenomectomy) led to improved vision and no recurrence in three patients, highlighting the importance of accurate diagnosis and treatment.

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Area of Science:

Endocrinology
Neurosurgery
Pathology

Background:

Pituitary adenomas are common pituitary tumors.
Pituitary oncocytomas represent a rare subtype requiring specific diagnostic and management strategies.

Observation:

Three cases of pituitary oncocytomas were identified among 102 pituitary adenoma patients.
Tumor histology revealed poorly developed organelles, hyperplastic and pleomorphic cells, swollen mitochondria, and scattered secretory granules.

Findings:

Transsphenoidal adenomectomy was performed for these pituitary oncocytomas.
Immunohistochemistry and electron microscopy confirmed the diagnosis.
All patients experienced gradual visual acuity improvement post-surgery with no recurrence observed.

Implications:

Accurate preoperative diagnosis of pituitary oncocytomas necessitates integrated endocrinological, neuroradiological, and clinical evaluation.
Surgical resection followed by postoperative radiotherapy is the recommended management approach for pituitary oncocytomas.

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