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Childhood cancer survivors--living beyond cure
P Kurkure1, S Achrekar, N Dalvi
1Department of Medical and Pediatric Oncology, Tata Memorial Hospital, Mumbai, India. kurkure@vsnl.com
Insights
Pediatric cancer survivors face significant long-term health challenges, with an estimated 50% developing disabilities. Addressing these late morbidities is crucial for ensuring survivors achieve a quality of life comparable to their peers.
Area of Science:
- Pediatric Oncology
- Cancer Survivorship Research
- Long-term Health Outcomes
Background:
- Improved treatments have increased survival rates for pediatric malignancies.
- The concept of a
- cured child
- now includes physical, mental, and emotional well-being alongside disease eradication.
- Delayed consequences of cancer therapies pose a significant long-term risk to survivors' quality of life.
Purpose of the Study:
- To highlight the growing concern of late morbidity in pediatric cancer survivors.
- To emphasize the importance of addressing long-term health issues beyond acute treatment complications.
- To underscore the potential impact of treatment-related disabilities on survivors' lives.
Main Methods:
- This abstract is based on a review of existing data and estimations regarding pediatric cancer survivorship.
- It synthesizes information on survival rates, treatment advancements, and projected survivor populations.
- The focus is on the anticipated long-term health consequences.
Main Results:
- The prevalence of childhood cancer survivors is increasing significantly.
- It is estimated that 50% of pediatric cancer survivors will experience disabilities affecting their quality of life.
- Late morbidities are a growing concern in this population.
Conclusions:
- While increased survival is a medical triumph, the long-term health of pediatric cancer survivors requires urgent attention.
- Addressing delayed consequences of therapy is essential for achieving a true
- cured child
- 's
- holistic well-being.
- Further research and supportive care strategies are needed to mitigate long-term morbidities and improve survivors' quality of life.
Abstract:
Advances in diagnosis and treatment along with improved supportive care have contributed to the current survival rates for pediatric malignancies. Recent concept of a truly "cured child" in pediatric oncology envisages not only a biological cure of the disease but a child on par with peers in growth and development physically and in achievements and aspirations, both mentally and emotionally. Because of the young age of these survivors and their potential for longevity, the delayed consequences of therapy may have a serious impact on their lives and family at large than do the acute complications of the cytotoxic therapies that they had experienced. Though figures from India are not available, it has been estimated that, in USA, the prevalence of childhood cancer survivors is expected to increase from 1 in 900 persons among young adults to 1:250 persons by 2010. Although this constitutes a remarkable medical achievement, the late morbidity in this growing survivor population has become an area for concern. It is estimated that 50% of the survivors are likely to develop disabilities that alter the quality of life.
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