Influence of acute exercise on urinary protein, creatinine, insulin-like growth factor-I (IGF-I) and IGF binding

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Günfer Turgut1, Bunyamin Kaptanoğlu, Sebahat Turgut

  • 1Physiology Department, Medical Faculty, Pamukkale University, Denizli, Turkey. gturgut@pamukkale.edu.tr

The Tohoku Journal of Experimental Medicine
|December 3, 2003
PubMed

Insights

Volleyball exercise increased urinary protein, creatinine, and insulin-like growth factor-I (IGF-I) in children. Urinary IGF-I binding protein-3 (IGFBP-3) levels remained unchanged, with no significant sex differences observed.

Area of Science:

  • Pediatric Endocrinology
  • Sports Science
  • Biochemistry

Background:

  • Insulin-like growth factor-I (IGF-I) is a crucial polypeptide hormone.
  • Insulin-like growth factor binding protein-3 (IGFBP-3) is the primary circulating carrier for IGF-I.
  • Understanding exercise-induced changes in these factors is important for pediatric health.

Purpose of the Study:

  • To investigate the impact of 2-hour volleyball exercise on urinary protein, creatinine, IGF-I, and IGFBP-3 concentrations in children.
  • To determine if these exercise-induced effects differ between male and female children.

Main Methods:

  • Recruitment of 27 children (13 female, 14 male), aged 10-13 years.
  • Measurement of weight and height.
  • Collection of urine samples pre- and post-exercise.
  • Analysis of urinary protein, creatinine, IGF-I, and IGFBP-3 levels.

Main Results:

  • Urinary concentrations of protein, creatinine, and IGF-I significantly increased after 2 hours of volleyball exercise.
  • Urinary IGFBP-3 concentrations showed no significant change post-exercise.
  • No statistically significant differences were found between boys and girls in the observed changes for any parameter.

Conclusions:

  • Volleyball exercise leads to increased urinary excretion of protein, creatinine, and IGF-I in children.
  • Urinary IGFBP-3 levels are not significantly affected by this type of exercise in this age group.
  • The physiological responses to 2 hours of volleyball exercise regarding these urinary markers are similar in both genders.

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