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Updated: Aug 15, 2026
14:39
Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
[Clinical course of asthmatics with severe asthma attack]
Y Ogawa1, S Sawamoto, H Nomoto
1Second Department of Medicine, Teikyo University School of Medicine, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi
|October 1, 1992
Summary
Severe asthma attacks requiring intensive care unit (ICU) admission show high mortality. Circulatory disturbance, not blood gas levels, was linked to fatal outcomes in bronchial asthma patients.
Area of Science:
- Pulmonology
- Critical Care Medicine
- Emergency Medicine
Context:
- Severe bronchial asthma attacks can necessitate intensive care unit (ICU) admission.
- Historical data from 1984-1989 on 39 ICU patients with severe asthma attacks.
- High mortality rate observed in this patient cohort.
Purpose:
- To analyze factors associated with mortality in severe bronchial asthma patients admitted to the ICU.
- To investigate the role of arterial blood gas levels and circulatory status in outcomes.
Summary:
- The study included 39 patients with severe asthma attacks and impaired consciousness requiring ICU admission.
- 16 deaths occurred, with most patients experiencing sudden collapse.
- Arterial blood oxygen levels (PaO2) did not significantly differ between survivors and non-survivors due to prior oxygen therapy.
- Marked circulatory disturbance was evident in fatal cases, while blood pressure maintenance aided recovery despite consciousness impairment.
Impact:
- Highlights the critical role of circulatory status in predicting outcomes for severe asthma exacerbations.
- Suggests that interventions focused on circulatory support may be crucial for improving survival rates.
- Informs critical care management strategies for patients with severe asthma attacks.
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