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Gastrointestinal stromal tumour--a paradigm shift in management of solid tumours
P P Bapsy1, K Prabhash, K G Babu
1Department of Medical Oncology, Kidwai Memorial Institute of Oncology, Bangalore.
The Journal of the Association of Physicians of India
|December 4, 2003
Abstract:
Gastrointestinal stromal tumour (GIST) till recently were non-responsive to all chemotherapy agents. With the advent of c-kit, diagnosis of GIST has become more specific. STI-571, a tyrosine kinase, has become one of the first targeted therapeutic agent tobe active in solid tumour. At present it is the only agent with substantial activity in GIST.