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Rotavirus gastroenteritis associated with afebrile convulsion in children: clinical analysis of 40 cases

Jeng-Juh Hung1, Hsin-Yi Wen, Meng-Hsiu Yen

  • 1Division of Pediatrics, Chang Gung Children's Hospital, 199, Tun-Hua North Road, Taipei 105, Taiwan, ROC.

Chang Gung Medical Journal
|December 4, 2003
PubMed

Insights

Afebrile seizures in children following rotavirus gastroenteritis are generally benign. Most children recover fully without long-term issues or the need for continuous anticonvulsant medication.

Area of Science:

  • Pediatrics
  • Neurology
  • Infectious Diseases

Background:

  • Rotavirus gastroenteritis is a common childhood illness.
  • Afebrile seizures can occur in children, sometimes associated with infections.
  • Understanding the link between rotavirus and seizures is crucial for pediatric care.

Purpose of the Study:

  • To investigate the clinical features of afebrile seizures in children hospitalized with rotavirus gastroenteritis.
  • To determine the outcomes and prognosis of these seizures.

Main Methods:

  • Retrospective study of hospitalized children under 18 with rotavirus gastroenteritis over 10 years.
  • Analysis of patients presenting with afebrile seizures, excluding those with prior seizure disorders or metabolic disturbances.
  • Statistical analysis using Chi-square, Kruskal-Wallis, and Mann-Whitney tests.

Main Results:

  • The incidence of afebrile seizures post-rotavirus gastroenteritis was 2.06% in the studied population.
  • The highest incidence (4.67%) was observed in children aged 1-2 years.
  • Most seizures occurred in clusters within 24 hours; electroencephalogram (EEG) findings were mostly normal and transient, with no status epilepticus observed.

Conclusions:

  • Afebrile seizures associated with rotavirus gastroenteritis in children have a benign clinical course.
  • Outcomes are generally satisfactory, with normal psychomotor development and no seizure recurrence in most cases.
  • Long-term anticonvulsant treatment is rarely required.
Abstract

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