Enteroviruses and type 1 diabetes mellitus
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Updated: Aug 13, 2026

Accelerated Type 1 Diabetes Induction in Mice by Adoptive Transfer of Diabetogenic CD4+ T Cells
Published on: May 6, 2013
Harry W Haverkos1, Narayana Battula, D Peter Drotman
1Center for Drug Evaluation and Research, Food and Drug Administration, HFD-530, 5600 Fishers Lane, Rockville, MD 20857, USA. haverkosh@cder.fda.gov
Abstract:
Despite decades of research, the etiology of type 1 diabetes mellitus (DM) is unknown. Several risk factors have been associated with type 1 DM, including viral infections, genetic predisposition, nutritional factors, and chemicals. Several investigators hypothesize that the etiologies of type 1 DM result from a complex interaction of genetic and environmental factors. In this paper we review the epidemiologic data linking enteroviruses to type 1 DM and discuss potential mechanisms of pathogenesis.
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