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Updated: Aug 29, 2026

Single Myofiber Isolation and Culture from a Murine Model of Emery-Dreifuss Muscular Dystrophy in Early Post-Natal Development
Published on: July 1, 2020
Merosin negative congenital muscular dystrophy: a short report
A M Ralte1, M C Sharma, S Gulati
1Department of Pathology, All India Institute of Medical Sciences, Ansarinagar, New Delhi - 110029, India.
Abstract:
We report a rare case of an infant with congenital muscular dystrophy who presented at birth with marked generalized hypotonia and normal mental development. Creatinine phosphokinase (CPK) level was markedly raised; however no white matter abnormalities were detected by brain imaging techniques. Immunohistochemical staining for merosin (laminin alpha 2) was negative, thereby confirming merosin-deficient congenital muscular dystrophy.
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