99Tcm and 111In leucocyte scintigraphy in inflammatory bowel disease

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D J Li1, S J Middleton, E P Wraight

  • 1Department of Nuclear Medicine, Addenbrooke's Hospital, Cambridge, UK.

Nuclear Medicine Communications
|December 1, 1992
PubMed

A comparative study of 99Tcm-hexamethylpropyleneamine oxime (HMPAO) and 111In leucocyte scintigraphy was performed in inflammatory bowel disease. Two hundred and thirty-four patients were studied, 146 had 99Tcm-HMPAO, 82 had 111In and six had both. The sensitivity, specificity and accuracy of the 99Tcm leucocyte scan were 96, 97 and 97%, respectively, and 96, 97 and 97%, respectively, for the 111In leucocyte scan. 99Tcm-HMPAO leucocytes demonstrated similar diagnostic accuracy to 111In-labelled leucocytes with improved image quality and reduced radiation dose.

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