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Updated: Aug 10, 2026
Neutrophil Isolation and Analysis to Determine their Role in Lymphoma Cell Sensitivity to Therapeutic Agents
Published on: March 25, 2016
[Clinical analysis of 282 patients with non-Hodgkin's lymphoma]
Shu-ping Chen1, Deng-shu Wu, Xie-lan Zhao
1Department of Hematology, Xiangya Hospital, Central South University, Changsha 410008, China.
Objective:
To analyze the classification, stage and prognosis of non-Hodgkin's lymphoma (NHL).
Methods:
Two hundred eighty two patients with NHL were retrospectively reviewed.
Results:
The complete remission (CR) rate and 5-year survival rate of B-cell NHL were higher than those of T-cell NHL(P < 0.05). There were significant differences in CR rate and 5-year survival rate among the low-grade, the intermediate-grade and the high-grade NHL(P < 0.05). The CR rate and 5-year survival rate of patients who were treated by the scheme of doxorubicin, cyclophosphamide, vincristine and prednisone (CHOP) were higher than those treated by the scheme of cyclophosphamide, vincristine, prednisone and etoposide (COP + VP16) (P < 0.05).
Conclusion:
Rational classification and staging play an important role in the prognosis of NHL. CHOP-based scheme may be regarded as the first choice and the standard scheme of treatment.
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