Population genomics: finding the variants of mass disruption

Pervasive interactions between exposures and polygenic risk can inform more effective clinical and behavioral interventions.

Nature genetics·2026

Trans-eQTLs reveal the architecture of human gene regulatory networks.

medRxiv : the preprint server for health sciences·2026

Gene expression profiling identifies potential biomarkers for vaso-occlusive episodes in sickle cell disease.

JCI insight·2026

Single-cell transcriptomics of multi-site cell therapy in osteoarthritis: Tissue-specific treatment correlations.

Molecular therapy. Nucleic acids·2026

Beyond Mendel: a call to revisit the genotype-phenotype map through new experimental paradigms.

Genetics·2026

Identification of Crohn's disease subtypes in single-cell RNA sequencing signatures of treatment-naive samples across the pediatric gastrointestinal tract.

Journal of Crohn's & colitis·2025

Seed mitochondria are equipped with cristae and a full proteome to kickstart germination.

Current biology : CB·2026

Topographic CA1 input shapes subicular spatial coding.

Current biology : CB·2026

Notch-mediated lateral inhibition is shaped by morphological differences to reinforce bias toward signal-sending or -receiving roles.

Current biology : CB·2026

Positional cues, not Notch, direct neuroblast selection during early neurogenesis in the Drosophila embryo.

Current biology : CB·2026

Preparatory encoding of intended movement in the human motor cortex and implications for brain-computer interfaces.

Current biology : CB·2026

Cold-gated potentiation of mechanotransduction supports touch sensation below 5°C in a mammalian hibernator.

Current biology : CB·2026

Newborn screening and biobanking for preventable genetic disorders in Mongolia: A developing country perspective.

Regenerative therapy·2026

Whole-genome resequencing with multidimensional annotation revealed pathogenic networks in sirenomelia.

Italian journal of pediatrics·2026

Human Loss-of-Function ZNRF3 Mutation Impairs Adipose Thermogenesis and Drives Subcutaneous Fat Expansion.

Diabetes·2026

Integrated genetic identification and molecular dynamics simulations in a novel LOXL3 genetic mutation associated with Stickler syndrome.

Frontiers in genetics·2026

The ZBTB16/CUL3/ROC1 ubiquitin ligase drives the degradation of pathogenic pendrin (SLC26A4) protein variants.

Journal of biomedical science·2026

Identification and functional characterization of a SUZ12 frameshift variant in a Chinese family with Imagawa-Matsumoto syndrome.

BMC medical genomics·2026

Related Experiment Videos

Population genomics: finding the variants of mass disruption

Related Concept Videos

Pervasive interactions between exposures and polygenic risk can inform more effective clinical and behavioral interventions.

Trans-eQTLs reveal the architecture of human gene regulatory networks.

Gene expression profiling identifies potential biomarkers for vaso-occlusive episodes in sickle cell disease.

Single-cell transcriptomics of multi-site cell therapy in osteoarthritis: Tissue-specific treatment correlations.

Beyond Mendel: a call to revisit the genotype-phenotype map through new experimental paradigms.

Identification of Crohn's disease subtypes in single-cell RNA sequencing signatures of treatment-naive samples across the pediatric gastrointestinal tract.

Seed mitochondria are equipped with cristae and a full proteome to kickstart germination.

Topographic CA1 input shapes subicular spatial coding.

Notch-mediated lateral inhibition is shaped by morphological differences to reinforce bias toward signal-sending or -receiving roles.

Positional cues, not Notch, direct neuroblast selection during early neurogenesis in the Drosophila embryo.

Preparatory encoding of intended movement in the human motor cortex and implications for brain-computer interfaces.

Cold-gated potentiation of mechanotransduction supports touch sensation below 5°C in a mammalian hibernator.

Newborn screening and biobanking for preventable genetic disorders in Mongolia: A developing country perspective.

Whole-genome resequencing with multidimensional annotation revealed pathogenic networks in sirenomelia.

Human Loss-of-Function ZNRF3 Mutation Impairs Adipose Thermogenesis and Drives Subcutaneous Fat Expansion.

Integrated genetic identification and molecular dynamics simulations in a novel LOXL3 genetic mutation associated with Stickler syndrome.

The ZBTB16/CUL3/ROC1 ubiquitin ligase drives the degradation of pathogenic pendrin (SLC26A4) protein variants.

Identification and functional characterization of a SUZ12 frameshift variant in a Chinese family with Imagawa-Matsumoto syndrome.

Related Experiment Videos

Population genomics: finding the variants of mass disruption

Related Concept Videos

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