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The Maternal Phenylketonuria International Study: 1984-2002

Richard Koch1, William Hanley, Harvey Levy

  • 1Childrens Hospital of Los Angeles and the University of Southern California School of Medicine, Los Angeles, California 90027, USA. rkoch8@earthlink.net

Pediatrics
|December 5, 2003
PubMed
Summary

Early dietary control of phenylalanine (Phe) in pregnant women with hyperphenylalaninemia (HPA) significantly reduces offspring morbidity. Achieving Phe levels between 120-360 micromol/L by 8-10 weeks gestation is crucial for optimal birth outcomes.

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