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[Chronic diarrhea in malabsorption].

¹Medizinische Poliklinik, Julius-Maximilians-Universität Würzburg Klinikstrasse 6-8, D-97070 Würzburg. al-taie.medpoli@mail.uni-wuerzburg.de

MMW Fortschritte Der Medizin

|December 6, 2003

Summary

Chronic diarrhea with malassimilation presents a diagnostic challenge, requiring a comprehensive approach. Evaluation involves patient history, clinical exams, lab tests, imaging, and specialized function tests for accurate diagnosis.

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Area of Science:

Gastroenterology
Internal Medicine
Diagnostic Medicine

Background:

Chronic diarrhea and malassimilation are indicative of various gastrointestinal disorders.
Conditions include celiac disease, lactose intolerance, and inflammatory bowel disease.
Accurate diagnosis is crucial for effective patient management.

Purpose of the Study:

To outline the diagnostic strategies for chronic diarrhea with malassimilation.
To emphasize the multi-faceted approach required for clarifying the underlying cause.

Main Methods:

Comprehensive patient history and clinical examination.
Orientating and specific laboratory investigations.
Imaging procedures such as ultrasound and endoscopy.
Specialized function tests including xylose-tolerance, H2 breath, and pancreas function tests.

Main Results:

The diagnostic process integrates multiple clinical and investigative modalities.
A stepwise approach, from basic to specialized tests, is often necessary.
No single test is universally diagnostic; a combination is typically employed.

Conclusions:

Diagnosing chronic diarrhea with malassimilation necessitates a systematic and thorough evaluation.
The integration of clinical assessment, laboratory workup, imaging, and functional testing is key.
Tailoring the diagnostic pathway to the individual patient presentation improves diagnostic yield.

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