Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Automatic post-implant needle reconstruction algorithm to characterize and improve implant robustness analyses.

Louis Archambault1, Luc Beaulieu, Dragan Tubic

  • 1Départment de Radio-Oncologie, Centre de Recherche en Cancérologie, Hôtel-Dieu de Quebec, 11 côte du palais, Québec, QC G1R 2J6, Canada.

Medical Physics
|December 6, 2003
PubMed
Summary

A new simulated annealing algorithm automates post-implant seed reconstruction in brachytherapy. This fast, accurate method improves treatment quality analysis and understanding of dose coverage, even with seed loss.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

High-performance dosimetric gel for low-dose-rate 3D-printed brachytherapy devices.

Physics in medicine and biology·2026
Same author

Biomarkers for Precision Prognosis in Prostate Cancer: Imaging, Molecular, and Integrated Approaches.

Cancers·2026
Same author

Evaluation of the hyperspectral multicomponent calibration for plastic scintillation dosimetry.

Physics in medicine and biology·2026
Same author

Pelvic nodes ultra-hypo fractionated versus conventionally fractionated IMRT with HDR brachytherapy in prostate cancer: interim analysis of a collaborative multi-institutional non-inferiority phase 3 trial (PCS-XI, NCT05820633).

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2026
Same author

Assessing inter-observer variability in prostate and GTV segmentation on mpMRI: A comparison between radiation oncologists and AI-based method.

Journal of applied clinical medical physics·2026
Same author

Robust external-beam calibration of plastic scintillation detectors and uncertainty analysis for<i>in-vivo</i>dosimetry in HDR brachytherapy.

Physics in medicine and biology·2026

Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Computational Biology

Background:

  • Post-implant analysis is crucial for assessing treatment quality in permanent implant brachytherapy.
  • Seed migration, edema, and procedural factors can compromise dose coverage.
  • Manual seed cluster reconstruction is time-consuming and labor-intensive.

Purpose of the Study:

  • To develop an automated method for reconstructing post-implant brachytherapy seed clusters.
  • To facilitate accurate post-implant analysis and feedback on treatment quality.
  • To enable better understanding of dose coverage variations and seed behavior.

Main Methods:

  • A simulated annealing algorithm was developed for automatic seed reconstruction.
  • The algorithm was tested on 21 clinical cases and 58 synthetic datasets.

Related Experiment Videos

  • Performance was evaluated based on speed, accuracy, and seed matching to planned positions.

    • Main Results:

    • The automated reconstruction process is fast (30-60 seconds) and successful, even with up to 5% seed loss.
    • Results from clinical cases matched manual reconstructions precisely.
    • For medium seed density, 97% of seeds were matched to the correct needle and 89% to the correct planned position.

    Conclusions:

    • The simulated annealing algorithm provides an efficient and accurate tool for post-implant brachytherapy analysis.
    • This method aids in understanding dose inhomogenities, performing realistic simulations, and identifying specific seed characteristics.