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Published on: October 11, 2024

Nonreplicating DNA viral vectors for suicide gene therapy: the adenoviral vectors

Masato Yamamoto1, David T Curiel

  • 1Division of Human Gene Therapy, Department of Medicine, Gene Therapy Center, University of Alabama at Birmingham, Birmingham, AL, USA.

Methods in Molecular Medicine
|December 6, 2003
PubMed
Abstract

No abstract available in PubMed .

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Gene Therapy

Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be inserted. The...