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Microcystic adnexal carcinoma with lymph node metastasis
Masanori Ban1, Shigeyuki Sugie, Hideki Kamiya
1Department of Dermatology, Hashima City Hospital, Hashima, Japan. masanoriban@k5.dion.ne.jp
Dermatology (Basel, Switzerland)
|December 6, 2003
Summary
Microcystic adnexal carcinoma (MAC), typically on the face, rarely spreads. This case highlights axillary MAC with recurrence and lymph node metastasis, suggesting potential for aggressive behavior.
Area of Science:
- Dermatopathology
- Surgical Oncology
- Oncology
Background:
- Microcystic adnexal carcinoma (MAC) is a rare skin appendage tumor.
- MAC predominantly affects the head and neck region.
- Metastasis from MAC is considered uncommon.
Observation:
- A case of MAC occurred in the axilla of a 63-year-old male.
- The patient experienced local recurrence 11 months post-excision.
- Metastatic tumor cells were found in two axillary lymph nodes.
Findings:
- The recurrent MAC showed typical histology centrally and a mixed pattern peripherally.
- Metastasis to lymph nodes was confirmed, challenging the notion of MAC's rarity in metastasis.
- The recurrent lesion's histology raises suspicion for transformation into a higher-grade carcinoma.
Implications:
- This case expands the known anatomical sites for MAC.
- It underscores the potential for MAC metastasis, even to lymph nodes.
- Further research is warranted to understand MAC's metastatic potential and prognostic factors.