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Related Experiment Videos

Hyalinizing spindle cell tumor with giant rosettes: a case report.

Sheau-Fang Yang1, Chiang-Shin Liu, Chee-Yin Chai

  • 1Department of Pathology, Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, Taiwan.

The Kaohsiung Journal of Medical Sciences
|December 9, 2003
PubMed
Summary

Hyalinizing spindle cell tumor with giant rosettes (HSCTGR) is a rare, low-grade sarcoma. Wide surgical excision and long-term monitoring are recommended for this indolent tumor, now considered a variant of low-grade fibromyxoid sarcoma.

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RETRACTED: Cheng et al. High PGC-1α Expression as a Poor Prognostic Indicator in Intracranial Glioma. <i>Biomedicines</i> 2024, <i>12</i>, 979.

Biomedicines·2025

Area of Science:

  • Oncology
  • Pathology
  • Surgical Oncology

Background:

  • Hyalinizing spindle cell tumor with giant rosettes (HSCTGR) is a rare low-grade sarcoma.
  • It is characterized by giant rosette-like structures and fibromyxoid stroma.
  • HSCTGR is now considered a variant of low-grade fibromyxoid sarcoma.

Observation:

  • A case of HSCTGR in the deep soft tissue of the left knee in a 50-year-old woman is presented.
  • The tumor exhibited characteristic giant rosettes with collagen cores.
  • The patient's tumor showed indolent behavior.

Findings:

  • Wide excision is the recommended treatment for HSCTGR.
  • Long-term follow-up is crucial for managing this tumor.
  • The case aligns with the current classification of HSCTGR as a variant of low-grade fibromyxoid sarcoma.

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Implications:

  • This case contributes to the understanding of HSCTGR presentation and management.
  • Highlights the importance of accurate diagnosis and surgical planning for rare sarcomas.
  • Emphasizes the need for continued research into the behavior and treatment of low-grade fibromyxoid sarcoma variants.