Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Area-specific amblyopic effects in human occipitotemporal object representations.

Y Lerner1, P Pianka, B Azmon

  • 1Weizmann Institute of Science, Rehovot, 76100, Israel.

Neuron
|December 9, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Electrophysiological Correlates of the Clinical Benefit Induced by Transcranial Magnetic Stimulation for Alcohol Use Disorder.

Biological psychiatry·2025
Same author

Investigating two mobile just-in-time adaptive interventions to foster psychological resilience: research protocol of the DynaM-INT study.

BMC psychology·2023
Same author

Are intravitreal injections essential during the COVID-19 pandemic? Global preferred practice patterns and practical recommendations.

International journal of retina and vitreous·2022
Same author

Intranasal dexmedetomidine in healthy beagles: An echocardiographic and pharmacokinetic/pharmacodynamic study.

Veterinary journal (London, England : 1997)·2019
Same author

Sleepless and desynchronized: Impaired inter trial phase coherence of steady-state potentials following sleep deprivation.

NeuroImage·2019
Same author

Herpes Corneæ and Virus Infection.

Glasgow medical journal·2018

Early visual experience shapes high-order visual cortex. In amblyopia (reduced vision), face processing areas show severe disconnection from the affected eye, unlike building-related areas.

Area of Science:

  • Neuroscience
  • Developmental Neuroscience
  • Visual Perception

Background:

  • The role of early visual input in developing high-order visual areas remains unclear.
  • Amblyopia, a developmental disorder causing reduced central vision, offers a model to study this.
  • Prior research noted functional changes in early visual areas of amblyopes.

Purpose of the Study:

  • To investigate how early visual experience influences the development of high-order visual areas.
  • To examine object-related processing in the occipitotemporal cortex of individuals with amblyopia.

Main Methods:

  • Utilized functional magnetic resonance imaging (fMRI) in human participants with amblyopia.
  • Assessed functional connectivity and activation patterns in response to visual stimuli.

Related Experiment Videos

  • Compared responses in face-selective and building-selective cortical regions.

    • Main Results:

    • Observed a selective deficit in high-order object-related cortex in amblyopia.
    • Found severe disconnection between the amblyopic eye and face-related cortical areas.
    • Building-related cortical regions showed largely normal function, indicating specificity of the deficit.

    Conclusions:

    • Early visual experience is critical for the normal development of specialized visual processing streams.
    • The findings highlight differential computational roles within object-related visual areas.
    • Face processing regions appear particularly sensitive to visual input quality during development.