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Updated: Aug 29, 2026

Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way
Published on: May 10, 2021
[Histological and cytopathological cancer specimens: good practice in operating room]
L Benoit1, P Favoulet, F Collin
1Service de chirurgie, centre G.-F.-Leclerc, 1, rue du Professeur-Marion, BP 77980, 21079 Dijon cedex, France. lbenoit@dijon.fnclcc.fr
Abstract:
Concerning good practice for the management of histological cancer specimen, the main recommendations concern: (1) the quality of transmission in information between professionals; (2) the necessity of fresh, unfractionated, oriented surgical samples; (3) the importance of an appropriate storage condition for samples collected for extemporaneous examination, freezing or cell culture; (4) the quality of the deep freezer at temperatures of -80 degrees C or liquid nitrogen for frozen samples storage; (5) the importance of fixing tissues shortly after sample collection in buffered Formal solution in order to prevent cell lysis.
