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Published on: May 19, 2022
The use of a distal occlusion balloon protection device in acute coronary syndrome
Steven S L Li1, C W Lam, Y C So
1Division of Cardiology, Department of Medicine, Queen Elizabeth Hospital, Kowloon, Hong Kong. listevensl@yahoo.com
Insights
The PercuSurge GuardWire Plus system demonstrated safety and feasibility as a distal protection device during percutaneous coronary intervention for acute coronary syndrome and myocardial infarction patients.
Area of Science:
- Cardiology
- Interventional Cardiology
- Medical Devices
Background:
- Acute coronary syndrome (ACS) and acute myocardial infarction (AMI) are critical cardiovascular conditions.
- Percutaneous coronary intervention (PCI) is a common treatment, but distal embolization remains a concern.
- Distal protection devices aim to mitigate risks during PCI.
Purpose of the Study:
- To evaluate the early clinical experience with the PercuSurge GuardWire Plus system.
- To assess the safety and feasibility of this distal protection device in ACS and AMI patients undergoing PCI.
Main Methods:
- A prospective study involving 43 patients with ACS/AMI undergoing PCI.
- The PercuSurge GuardWire Plus system was used as a distal protection device.
- Outcomes included procedural success, device deployment, and major adverse clinical events (MACE).
Main Results:
- The GuardWire Plus system was successfully deployed in 41 of 43 patients.
- Post-PCI, TIMI III flow was achieved in all 41 patients with native coronary vessels.
- No procedure-related or device-related MACE occurred during the procedure or at 30-day follow-up.
Conclusions:
- The PercuSurge GuardWire Plus system is safe and feasible for use in patients with ACS and AMI.
- The device effectively facilitated successful PCI with favorable hemodynamic outcomes.
- This early experience suggests the GuardWire Plus system is a valuable tool in managing high-risk PCI patients.
Abstract:
We report our early experience in using the PercuSurge GuardWire Plus system as a distal protection device in patients with acute coronary syndrome and acute myocardial infarction. Forty-three patients received percutaneous coronary intervention with the GuardWire Plus system. Thirteen had unstable angina, five had non-Q myocardial infarction and 25 had ST segment elevation myocardial infarction. Forty-one target lesions were in native coronary vessels and two were in saphenous vein grafts. Total occlusion occurred in 18 patients. The mean occlusion time by the distal protective balloon was 262.8 +/- 114.1 s. Preoperatively, TIMI 0 flow was present in 18, TIMI II flow in two and TIMI III flow in 23 patients. Post-operatively, TIMI II and TIMI III flow were established in two and 41 patients, respectively. All procedures were successful and the GuardWire Plus system was successfully deployed in all but two patients. There was no procedure-related major adverse clinical event. There was no major adverse clinical event at 30 days. There was no device-related complication. We believe that the GuardWire Plus system is safe and feasible in patients with acute coronary syndrome and acute myocardial infarction.
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