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Related Experiment Video

Updated: Jul 1, 2026

Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice
07:07

Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice

Published on: January 12, 2017

[Using mineral trioxide aggregate as a direct pulp-capping material in dogs].

Ya-qin Zhu1, Lie Xia

  • 1Department of Oral Medicine, Ninth People's Hospital, Shanghai Second Medical University, Shanghai 200011, China. zhu1590@hotmail.com

Shanghai Kou Qiang Yi Xue = Shanghai Journal of Stomatology
|December 10, 2003
PubMed
Summary

Mineral Trioxide Aggregate (MTA) demonstrated superior results compared to Dycal in promoting healing and reducing inflammation after direct pulp capping in dogs. MTA is a promising material for vital pulp therapy.

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Area of Science:

  • Biomaterials Science
  • Dental Research
  • Regenerative Medicine

Context:

  • Vital pulp therapy aims to preserve the vitality of the dental pulp.
  • Direct pulp capping is a procedure to repair exposed pulp tissue.
  • Biocompatible materials are crucial for successful pulp regeneration.

Purpose:

  • To compare the efficacy of Mineral Trioxide Aggregate (MTA) and Dycal as direct pulp-capping agents.
  • To evaluate pulpal inflammation and dentin bridge formation following pulp exposure in dogs.
  • To assess the potential of MTA and Dycal in vital pulp therapy.

Summary:

  • Histological examination of canine teeth subjected to direct pulp capping with MTA or Dycal was performed.
  • Mineral Trioxide Aggregate (MTA) showed significantly less pulpal inflammation and enhanced dentin bridge formation compared to Dycal.

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Last Updated: Jul 1, 2026

Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice
07:07

Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice

Published on: January 12, 2017

Inducing Apical Periodontitis in Mice
10:26

Inducing Apical Periodontitis in Mice

Published on: August 6, 2019

Accessing the Cytotoxicity and Cell Response to Biomaterials
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Published on: July 8, 2021

  • All MTA-treated samples exhibited dentin bridge formation, while only two Dycal-treated samples did.

    • Impact:

    • Mineral Trioxide Aggregate (MTA) exhibits excellent biocompatibility and promotes dentinogenesis.
    • MTA proves to be a superior material for direct pulp capping in vital pulp therapy.
    • Findings support the use of MTA in clinical dental applications for pulp preservation.