Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

OSAS in craniofacial syndromes: an unsolved problem.

L J Hans Hoeve1, Marloes Pijpers, Koen F M Joosten

  • 1Department of Paediatric Otorhinolaryngology, Sophia Children's Hospital, Erasmus MC, Dr. Molewaterplein 60, 3015 GJ, Rotterdam, The Netherlands. l.j.hoeve@erasmusmc.nl

International Journal of Pediatric Otorhinolaryngology
|December 10, 2003
PubMed
Summary

Obstructive Sleep Apnea syndrome (OSAS) is common in craniofacial syndromes but often missed. Early diagnosis using polysomnography and airway endoscopy, followed by prompt treatment, is crucial to prevent severe complications in these patients.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Critically Ill Children Show Disrupted Sleep Patterns and Atypical Electroencephalograms: An Observational Cohort Study.

Acta paediatrica (Oslo, Norway : 1992)·2026
Same author

Diurnal rhythms in melatonin and cortisol in very preterm human milk.

Frontiers in nutrition·2026
Same author

Lifestyle behaviours in children born extremely preterm at 2 years: a comparison to a Dutch reference population.

European journal of pediatrics·2026
Same author

An Innovative Transitional Care Unit for Hospital to Home Transition of Children With Medical Complexity: A Qualitative Study of Parents' Experiences.

Child: care, health and development·2026
Same author

Hypophosphatemia as a biomarker of metabolic intolerance to enhanced nutrition in the PICU: a secondary analysis of the PEPaNIC RCT.

Critical care (London, England)·2026
Same author

Chrononutrition: 24-hour variation in macronutrients in very preterm human milk.

Early human development·2026

Area of Science:

  • Medical Science
  • Pediatric Medicine
  • Genetics

Background:

  • Obstructive Sleep Apnea syndrome (OSAS) frequently affects individuals with craniofacial syndromes.
  • Diagnosis and treatment of OSAS in this population are often delayed or overlooked.
  • Craniofacial syndromes like Apert, Crouzon, and Pfeiffer are associated with a high incidence of airway obstruction.

Purpose of the Study:

  • To investigate diagnostic methods for OSAS in patients with craniofacial syndromes.
  • To review and compare treatment options for OSAS in this specific patient group.
  • To highlight the importance of early recognition and intervention for OSAS in craniofacial anomalies.

Main Methods:

  • Retrospective study of 72 patients with Apert, Crouzon, or Pfeiffer syndrome.

Related Experiment Videos

  • Analysis of diagnostic procedures including polysomnography (PSG) and airway endoscopy.
  • Literature review to compare findings with existing research on OSAS in craniofacial syndromes.

    • Main Results:

    • Polysomnography (PSG) and airway endoscopy are consistently identified as key diagnostic tools.
    • Therapeutic approaches for OSAS in craniofacial syndromes show considerable diversity.
    • A high incidence of unrecognized OSAS was observed in the studied cohort.

    Conclusions:

    • Early and accurate diagnosis of OSAS is essential for patients with craniofacial syndromes.
    • Prompt therapeutic interventions can mitigate serious health complications associated with OSAS.
    • Standardized diagnostic and treatment protocols may improve outcomes for these vulnerable patients.