Related Experiment Video
Updated: Aug 29, 2026
Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
Detection of early visual field loss in glaucoma using frequency-doubling perimetry and short-wavelength automated
John A Landers1, Ivan Goldberg, Stuart L Graham
1Eye Associates and Save Sight Institute, Sydney University, Sydney, New South Wales, Australia. landers@lisp.com.au
Objective:
To investigate whether frequency-doubling perimetry (FDP) predicts future visual field loss with achromatic automated perimetry (AAP), just as it may be predicted with short-wavelength automated perimetry (SWAP).
Methods:
We recruited 62 patients selectively from an urban glaucoma practice. At the commencement of the study, each patient had ocular hypertension with normal visual fields on AAP. Baseline SWAP and FDP were performed to determine whether underlying earlier visual field loss was present. Patients were then followed up prospectively for 3 years with annual AAP, SWAP, and FDP. Main Outcome Measure The development of visual field loss on AAP.
Results:
Nine subjects had abnormal SWAP findings and 10 had abnormal FDP findings. At the conclusion of the study, field loss on AAP developed in 5, all of whom had preexisting abnormal SWAP and FDP results. No AAP visual field loss developed in patients with a normal SWAP or FDP. The rate of development of visual field loss on AAP was therefore significantly greater for those with abnormal SWAP (chi21 = 40.83; P<.001) and abnormal FDP findings (chi21 = 32.76; P<.001) than for those with normal SWAP and FDP findings.
Conclusion:
In the same way that SWAP may predict AAP visual field loss, FDP may also detect field loss earlier than AAP.
