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Quantification of Ile-Ser-Bradykinin degradation in human serum and ascites
J Rehbock1, C Steinhauser, A Hermann
1Frauenklinik der Universität München, Deutschland.
Agents and Actions. Supplements
|January 1, 1992
Abstract:
A leucine aminopeptidase (LAP) and a carboxypeptidase (CP) activity in human serum and malignant ascites degrade Ile-Ser-Bradykinin (ISB = T-Kinin) in two catalytic steps to desArg9Bradykinin. The catalytic activity in serum is always higher than in ascites. In serum the carboxypeptidase activity is higher than the LAP activity whereas in ascites the two activities are not different.