Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Facing extremes: archaeal surface-layer (glyco)proteins.

Jerry Eichler1

  • 1Department of Life Sciences, Ben Gurion University, PO Box 653, Beersheva 84105, Israel.

Microbiology (Reading, England)
|December 10, 2003
PubMed
Summary

Archaea possess unique surface layer proteins that enable survival in extreme environments. These proteins are crucial for maintaining structural integrity and offer insights into archaeal protein biosynthesis and export.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Distinct properties of Halobacterium salinarum Agl32, an archaeal D-glucuronyl C5-epimerase involved in N-glycosylation.

Glycobiology·2026
Same author

Only in Halobacterium salinarum: Sugar modifications unique to an archaeal N-linked glycan.

Carbohydrate research·2026
Same author

Identification of the D-glucuronyl C5-epimerase that introduces iduronic acid into N-linked glycans decorating archaeal glycoproteins.

Communications biology·2025
Same author

Two different sulfotransferases modify sugars of the N-linked tetrasaccharide decorating <i>Halobacterium salinarum</i> glycoproteins.

mBio·2025
Same author

N-glycosylation in Archaea - Expanding the process, components and roles of a universal post-translational modification.

BBA advances·2024
Same author

Perturbed N-glycosylation of Halobacterium salinarum archaellum filaments leads to filament bundling and compromised cell motility.

Nature communications·2024

Area of Science:

  • Microbiology
  • Biochemistry
  • Structural Biology

Background:

  • Archaea are extremophiles thriving in harsh conditions.
  • Their surface layer (glyco)proteins must withstand extreme physical challenges.
  • Understanding these proteins is key to archaeal survival strategies.

Purpose of the Study:

  • To review recent advances in studying archaeal surface-layer (glyco)proteins.
  • To highlight protein strategies for extreme environment survival.
  • To elucidate archaeal protein biosynthesis, modification, and export.

Main Methods:

  • Literature review of recent studies on archaeal surface layer proteins.
  • Analysis of structural and functional adaptations to extreme environments.
  • Examination of biosynthesis pathways including glycosylation and lipid modification.

Main Results:

  • Archaeal surface layer proteins exhibit diverse structures and assembly mechanisms.
  • Specific adaptations allow protein stability in high salinity, temperature, and acidity.
  • These proteins are involved in crucial cellular processes like export and modification.

Conclusions:

  • Archaeal surface layer proteins are vital for extremophile survival.
  • Studying these proteins provides insights into fundamental biological processes.
  • Further research can uncover novel biotechnological applications.

Related Experiment Videos