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Chorioangioma and its severe infantile sequelae: case report
Ron Maymon1, Gratiana Hermann, Orit Reish
1Department of Obstetrics and Gynecology, Assaf Harofe Medical Center, Zerifin, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. intposgr@post.tau.ac.il
Prenatal Diagnosis
|December 10, 2003
Summary
Prenatal diagnosis of chorioangioma, a rare placental tumor, was made due to elevated maternal serum alpha-fetoprotein. The infant developed complications, highlighting the link between placental and fetal angiomas.
Area of Science:
- Obstetrics and Gynecology
- Fetal Medicine
- Pathology
Background:
- Chorioangiomas are rare placental tumors.
- Elevated maternal serum alpha-fetoprotein can indicate placental abnormalities.
- Prenatal diagnosis is crucial for managing potential complications.
Observation:
- A 30-year-old woman presented with elevated maternal serum alpha-fetoprotein (AFP), hCG, and uE3.
- Ultrasound revealed a 5x5 cm placental lesion consistent with chorioangioma.
- The pregnancy progressed with developing polyhydramnios and fetal cardiomegaly.
Findings:
- A female infant was born with cutaneous and liver angiomatosis.
- The infant experienced cardiac failure and infection, leading to death at one month.
- The case demonstrates a link between placental and fetal angiomas.
Implications:
- This case highlights the interrelationship between placental and fetal angiomas.
- Such conditions can lead to severe infantile sequelae.
- Early prenatal diagnosis and monitoring are vital for improved outcomes.