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Fetomaternal Doppler sonography nomograms.

A K Ertan1, H J Hendrik, H A Tanriverdi

  • 1Saarland University Medical School, Department of Obstetrics and Gynecology, Homburg/Saar, Germany. ertan@uniklinik-saarland.de

Clinical and Experimental Obstetrics & Gynecology
|December 11, 2003
PubMed
Summary

This study establishes Doppler flow velocity nomograms for pregnant women, crucial for differentiating normal from abnormal pregnancies. These gestational age-specific curves aid obstetric clinics in accurate fetal assessments.

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Area of Science:

  • Obstetrics and Gynecology
  • Fetal Medicine
  • Diagnostic Ultrasound

Background:

  • Doppler ultrasound is vital for assessing fetal well-being.
  • Establishing normative data is essential for accurate clinical interpretation.
  • Existing nomograms may not fully capture gestational age-specific changes.

Purpose of the Study:

  • To create Doppler flow velocity nomograms for obstetric use.
  • To analyze the methodology for constructing clinical Doppler sonography nomograms.
  • To provide reference curves for umbilical artery, fetal aorta, middle cerebral artery, and uterine artery Doppler indices.

Main Methods:

  • A cross-sectional study of 602 flow results from 370 pregnant women.
  • Gestational ages confirmed by early sonography (<14 weeks).

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  • Exclusion of high-risk pregnancies (placental insufficiency, fetal distress, etc.).
  • Calculation of 5th, 10th, 50th, 90th, and 95th percentiles for Doppler indices (S/D ratio, RI, PI) every two weeks.
  • Main Results:

    • Uteroplacental flow velocities stabilized after 22-24 weeks.
    • Fetal vessel velocity waveforms changed significantly after 22-24 weeks.
    • Impedance in the umbilical artery and middle cerebral artery decreased in the third trimester.
    • Resistance in the descending fetal aorta remained relatively constant.

    Conclusions:

    • Doppler velocity waveforms change with advancing gestational age.
    • Gestational age-adapted nomograms are necessary for accurate Doppler studies.
    • These presented norm-curves offer practical tools for clinical obstetrics to distinguish normal from abnormal pregnancies.