Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Peripheral neuropathy and cancer.

Arthur D Forman1

  • 1Consultation Neurology Service, University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Avenue, Houston, TX 77030, USA. aforman@mdanderson.org

Current Oncology Reports
|December 11, 2003
PubMed
Summary

Peripheral neuropathy significantly impacts patient quality of life and treatment options. Understanding its mechanisms and new treatments can help manage this condition in cancer patients.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Seizures and epilepsy in cancer: etiologies, evaluation, and management.

Current oncology reports·2008
Same author

A multicenter phase II trial of intrathecal topotecan in patients with meningeal malignancies.

Neuro-oncology·2008
Same author

Neoplastic meningitis in patients with adenocarcinoma of the gastrointestinal tract.

Cancer·2005
Same author

Tacrolimus-associated posterior reversible encephalopathy syndrome after allogeneic haematopoietic stem cell transplantation.

British journal of haematology·2003

Area of Science:

  • Oncology
  • Neurology
  • Pharmacology

Background:

  • Peripheral neuropathy is a common and debilitating side effect of cancer treatment.
  • Clinicians face challenges in recognizing and managing the diverse symptoms of neuropathy.
  • Increasing use of neurotoxic agents in cancer therapy exacerbates this issue.

Purpose of the Study:

  • To review current knowledge on the mechanisms of chemotherapy-induced peripheral neuropathy (CIPN).
  • To discuss emerging treatment strategies for managing neuropathy in cancer patients.
  • To improve the quality of life for patients undergoing neurotoxic cancer therapies.

Main Methods:

  • Literature review of recent studies on neuropathy mechanisms.
  • Analysis of current and novel therapeutic approaches.
  • Synthesis of clinical management guidelines.

Main Results:

  • Advances in understanding neuropathic disease mechanisms are providing new insights.
  • Several promising treatments are being investigated to mitigate nerve damage.
  • Effective management strategies can potentially reduce the impact of neuropathy.

Conclusions:

  • Enhanced understanding of neuropathy mechanisms offers hope for better patient outcomes.
  • New therapeutic interventions may help minimize treatment limitations caused by neuropathy.
  • Addressing peripheral neuropathy is crucial for maintaining quality of life in cancer patients.

Related Experiment Videos