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Voiding impairment after prostate biopsy: does tamsulosin treatment before biopsy decrease this morbidity?

Murat Bozlu1, Ercüment Ulusoy, Erdal Doruk

  • 1Department of Urology, University of Mersin School of Medicine, Zeytinlibahce Caddesi, Turkey.

Urology
|December 11, 2003
PubMed
Summary
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Transrectal ultrasound (TRUS)-guided prostate biopsy can cause temporary voiding issues. Pre-procedure tamsulosin treatment significantly reduced post-biopsy voiding difficulties and improved urinary symptoms in patients.

Area of Science:

  • Urology
  • Medical Procedures
  • Pharmacology

Background:

  • Transrectal ultrasound (TRUS)-guided prostate biopsy is a common procedure.
  • Post-biopsy voiding impairment is a known complication.
  • Alpha(1)-blockers like tamsulosin are used to treat lower urinary tract symptoms.

Purpose of the Study:

  • To assess the link between TRUS-guided prostate biopsy and voiding impairment.
  • To determine if pre-biopsy tamsulosin improves post-procedure voiding outcomes.

Main Methods:

  • A prospective randomized study of 66 patients undergoing TRUS-guided prostate biopsy.
  • 33 patients received tamsulosin (0.4 mg daily) pre- and post-biopsy.
  • 33 patients served as a control group without tamsulosin.

Related Experiment Videos

  • International Prostate Symptom Score (IPSS) and maximal flow rate (Qmax) were measured pre- and post-biopsy.

    • Main Results:

    • Tamsulosin group showed significantly lower rates of voiding difficulty on postbiopsy day 7 (9.09% vs. 42.42%).
    • Tamsulosin improved IPSS and Qmax in the treatment group compared to baseline.
    • Control group experienced significantly increased IPSS and decreased Qmax on postbiopsy day 7.

    Conclusions:

    • TRUS-guided prostate biopsy is associated with transient voiding impairment.
    • Pre-biopsy administration of tamsulosin can mitigate post-procedure voiding difficulties.
    • Tamsulosin may be a beneficial adjunct to reduce morbidity following prostate biopsy.