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Published on: May 19, 2020
Acquired mitral stenosis in a cat with hypertrophic cardiomyopathy
Naoyuki Takemura1, Kiyoshi Nakagawa, Noboru Machida
1Department of Veterinary Internal Medicine, Nippon Veterinary and Animal Science University, Musashino City, Tokyo, Japan.
Insights
This case study reveals that acquired mitral stenosis (MS) can develop alongside hypertrophic cardiomyopathy (HCM) in cats. Post-mortem examination confirmed fibrous tissue fusion causing MS in a cat with HCM.
Area of Science:
- Veterinary Cardiology
- Comparative Pathology
Background:
- Hypertrophic cardiomyopathy (HCM) is a common cardiac disease in cats.
- Mitral stenosis (MS) is a less common valvular heart disease, often congenital or secondary to other conditions.
Observation:
- A seven-year-old domestic shorthair cat presented with clinical signs suggestive of HCM and MS.
- Diagnostic imaging, including echocardiography, supported the initial diagnosis.
- Post-mortem examination revealed severe fibrous thickening and fusion of the chordae tendineae and mitral valve commissures.
Findings:
- The cat exhibited morphological changes consistent with HCM.
- Significant fibrous deposition led to complete chordal fusion, creating a restrictive inflow obstruction characteristic of acquired MS.
- This case demonstrates a unique pathological progression of acquired MS in conjunction with feline HCM.
Implications:
- This finding expands the understanding of potential complications associated with feline HCM.
- It highlights the importance of considering acquired MS in cats diagnosed with or suspected of having HCM.
- Further research into the mechanisms and prevalence of acquired MS in HCM cases is warranted.
Abstract:
A seven-year-old castrated male domestic shorthair cat was diagnosed with hypertrophic cardiomyopathy (HCM) and suspected mitral stenosis (MS) based on electrocardiography, thoracic radiographs and echocardiographic findings. Post-mortem examination of the heart revealed morphological features consistent with HCM. In addition, there was marked fibrous deposition on the surfaces of the chordae tendineae extending to both mitral valve leaflets, which caused total chordal fusion into pillars of fibrous tissue and fusion of the commissures. The present case indicates that acquired MS can occur in association with HCM in the cat.
Related Concept Videos
Mitral Stenosis I: Introduction
Mitral Stenosis II: Clinical features and Diagnostic Tests
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Mitral Stenosis III: Medical Management
Mitral Regurgitation I: Introduction
Mitral Valve Prolapse I: Introduction

