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Updated: Aug 29, 2026

Transurethral Instillation Procedure in Adult Male Mouse
Published on: November 2, 2017
Fetoscopic placement of a transurethral stent for intrauterine obstructive uropathy
Rainer Hofmann1, Tanja Becker, Matthias Meyer-Wittkopf
1Department of Urology, Medical School, Philipps-Universität Marburg, Germany. R.Hoffmann@med.uni-marburg.de
Purpose:
Fetal urinary obstructive uropathy and consecutive oligohydramnios result in a poor outcome. Usually renal insufficiency and life threatening lung hypoplasia have developed at term. We report a case of in utero fetal cystoscopy and successful placement of a transurethral vesico-amniotic Double-J (Medical Engineering Corp., New York, New York) stent. Indications, results and the potential benefits of different techniques are discussed.
Material And Methods:
A 36-year-old woman (primipara) was evaluated at week 26 due to a male fetus with bilateral hydronephrosis, massive distended bladder and an open posterior urethra. Using local anesthesia the fetal bladder was punctured, a 2.6 mm endoscope was inserted and a wire was advanced antegrade through the penis. A 2.8Fr Double-J stent was then placed between the bladder and amniotic cavity.
Results:
The bladder drained into the amnion, hydronephrosis disappeared and the lung developed normally. At week 37 a healthy infant was delivered who voided spontaneously.
Conclusions:
After careful selection of candidates for fetal intervention in obstructive uropathy direct vision fetoscopy and transurethral stent placement can be performed in patients with oligohydramnios, favorable urinary electrolytes and normal appearing kidneys.
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