Related Experiment Video

Updated: Aug 15, 2026

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China
08:42

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China

Published on: February 11, 2022

Fibrillation in patients subjected to coronary artery bypass grafting

Zhong-Kai Wu1, Tiina Iivainen, Erkki Pehkonen

  • 1Division of Cardiothoracic Surgery, Department of Surgery, Tampere University Hospital, Finland.

The Journal of Thoracic and Cardiovascular Surgery
|December 11, 2003
PubMed

Insights

Ischemic preconditioning significantly reduced the incidence of postoperative atrial fibrillation (AF) in patients undergoing coronary artery bypass grafting (CABG). This protective effect suggests ischemic preconditioning is a viable prophylactic method for preventing AF after CABG surgery.

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Critical Care Medicine

Background:

  • Atrial fibrillation is a common complication following coronary artery bypass grafting (CABG).
  • Ischemic preconditioning is known to protect against ischemia-reperfusion arrhythmias.
  • The efficacy of ischemic preconditioning in preventing post-CABG atrial fibrillation remains uninvestigated.

Purpose of the Study:

  • To determine if ischemic preconditioning can reduce the incidence of atrial fibrillation after coronary artery bypass grafting.

Main Methods:

  • Eighty-five patients undergoing CABG were randomized into an ischemic preconditioning group or a control group.
  • Continuous 24-hour Holter electrocardiography monitoring was performed from pre-operation to postoperative day two.
  • Atrial fibrillation was defined as any detected event during the monitoring period.

Main Results:

  • The incidence of atrial fibrillation was significantly lower in the ischemic preconditioning group (21.4%) compared to the control group (46.5%, P = .015).
  • Ischemic preconditioning, preoperative heart rate, and postoperative pulmonary capillary wedge pressure were identified as independent predictors of atrial fibrillation.
  • Patients experiencing atrial fibrillation had longer ICU stays and poorer hemodynamic outcomes.

Conclusions:

  • Post-CABG atrial fibrillation is linked to adverse postoperative outcomes.
  • Ischemic preconditioning effectively suppresses atrial fibrillation after CABG.
  • Ischemic preconditioning represents a promising prophylactic strategy for reducing postoperative atrial fibrillation.
Abstract

More Related Videos

A Model of Long-Term Ventricular Fibrillation in Isolated Rat Hearts07:56

A Model of Long-Term Ventricular Fibrillation in Isolated Rat Hearts

Published on: February 17, 2023

Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft05:25

Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft

Published on: September 15, 2023

Related Concept Videos

Disturbances in Heart Rhythm01:29

Disturbances in Heart Rhythm

Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
Dysrhythmias IV: Characteristics of Bradyarrhythmias01:18

Dysrhythmias IV: Characteristics of Bradyarrhythmias

Bradyarrhythmias are cardiac rhythm disorders characterized by a slower-than-normal heart rate, typically defined as fewer than 60 beats per minute. Some of which are discussed here:Sinus BradycardiaSinus bradycardia presents a heart rate lower than 60 beats per minute, with a regular rhythm originating from the SA node. The ECG typically shows normal P waves preceding each QRS complex, a normal PR interval (0.12 to 0.20 seconds), and a normal QRS duration (0.06 to 0.10 seconds).First-Degree AV...