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The echinoid immune system and the phylogenetic occurrence of immune mechanisms in deuterostomes
1Division of Biology, California Institute of Technology, Pasadena 91125.
Immunology Today
|September 1, 1992
Abstract:
In this article, Courtney Smith and Eric Davidson reinterpret the published data on immune function in lower deuterostomes and primitive chordates. It leads them to a new model of immune system phylogeny in which MHC-directed T-cell responses are the last to evolve and are not derived from subchordate self-nonself recognition systems.