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Updated: Aug 14, 2026
11:56
Fabrication and Operation of an Oxygen Insert for Adherent Cellular Cultures
Published on: January 7, 2010
The development of the modern oxygenator
1Cachet Medical Limited, Columbia Heights, Minnesota, USA.
The Annals of Thoracic Surgery
|December 12, 2003
Summary
Microporous hollow fiber oxygenators, dominant since the 1980s, ensure safe extracorporeal circulation. Advanced design tools like computational fluid dynamics have optimized their performance for clinical use.
Area of Science:
- Biomedical Engineering
- Cardiovascular Technology
Background:
- Extracorporeal circulation technology has evolved significantly since 1953.
- Early oxygenators paved the way for modern advancements in patient support.
Observation:
- Microporous hollow fiber oxygenators emerged in the early 1980s.
- These oxygenators feature blood flow outside the hollow fibers, becoming the industry standard.
Findings:
- The success of hollow fiber oxygenators is attributed to defined performance criteria.
- Computational fluid dynamics (CFD) has been instrumental in optimizing oxygenator design.
Implications:
- Modern oxygenators offer adequate performance for safe clinical application.
- Diverse manufacturers provide oxygenators with varying, yet sufficient, performance levels.
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