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Updated: Jun 30, 2026

A Melanoma Patient-Derived Xenograft Model

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Published on: May 20, 2019

[Becker's melanosis: a case report].

A Zárate-Moysén¹, H E Feregrino-Hernández, A Delgado-Fernández

¹División de Pediatría y Dermatología, Hospital General Dr. Manuel Gea González, México, D.F.

Boletin Medico Del Hospital Infantil De Mexico

|November 1, 1992

Summary

This summary is machine-generated.

Becker melanosis, a rare skin condition causing hyperpigmentation and hypertrichosis, is reported in a 4-year-old girl, the youngest case documented. This case highlights potential associations with developmental anomalies in early childhood.

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Area of Science:

Dermatology
Pediatric Dermatology
Genetics

Background:

Becker melanosis is a rare congenital skin disorder.
Characterized by hyperpigmentation and hypertrichosis, typically appearing during puberty.
Its association with developmental anomalies is increasingly recognized.

Observation:

A 4-year-old girl presented with Becker melanosis affecting her trunk and right leg.
This represents the youngest reported case in medical literature.
The affected leg exhibited minimal shortening.

Findings:

The patient displayed typical hyperpigmentation and hypertrichosis consistent with Becker melanosis.
The early onset and affected limb suggest a potential link to underlying developmental issues.
No nevus cells were observed, differentiating it from congenital nevi.

Implications:

This case expands the understanding of Becker melanosis presentation in infancy.
Highlights the importance of evaluating for associated developmental anomalies in pediatric cases.
Suggests further research into the genetic and developmental underpinnings of early-onset Becker melanosis.