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The MUSC DNA Microarray Database.

Gary L Argraves1, Jeremy L Barth, W Scott Argraves

  • 1Array Genetics, Inc., 59 Great Quarter Road, Newtown, CT 06482, USA.

Bioinformatics (Oxford, England)
|December 12, 2003
PubMed
Summary
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The Medical University of South Carolina (MUSC) DNA Microarray Database archives gene expression data. This publicly accessible resource allows researchers to interrogate and download DNA microarray data for scientific discovery.

Area of Science:

  • Bioinformatics
  • Genomics
  • Data Management

Background:

  • The Medical University of South Carolina (MUSC) developed a DNA Microarray Database.
  • This database serves as a web-accessible archive for DNA microarray data.

Purpose of the Study:

  • To create a centralized, publicly accessible repository for DNA microarray data.
  • To provide a model for other academic institutions developing similar data repositories.

Main Methods:

  • Utilized the micro ArrayDB system for data management.
  • Stored annotations and cRNA target information in a MySQL relational database.
  • Linked hybridization data (raw and normalized) to annotations.

Main Results:

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  • Established a web-accessible archive of DNA microarray data.
  • Enabled interrogation and downloading of gene expression data via a web browser.
  • Made data publicly available at the discretion of investigators.

    • Conclusions:

    • The MUSC DNA Microarray Database is a valuable online resource for gene expression data.
    • The database serves as a successful model for academic data repositories.