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MUTAGEN: multi-user tool for annotating genomes.

Kim Brügger¹, Peter Redder, Marie Skovgaard

¹Danish Archaea Centre, Institute of Molecular Biology, University of Copenhagen, Sølvgade 83H, DK-1307 Copenhagen K, Denmark. brugger@mermaid.molbio.ku.dk

Bioinformatics (Oxford, England)

|December 12, 2003

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MUTAGEN is a free, open-source prokaryotic genome annotation system. This software facilitates genome comparison and analysis through a web interface, aiding researchers in annotating microbial genomes.

Area of Science:

Bioinformatics
Genomics
Microbiology

Background:

MUTAGEN is an open-source software released under GPL.
The source code is available for download and contribution.

Purpose of the Study:

To introduce MUTAGEN, a free prokaryotic genome annotation system.
To highlight its features for genome analysis and user accessibility.

Main Methods:

Development of a web-interface for multi-user access.
Implementation of genome comparison, graphical browsers, and search functionalities.

Main Results:

MUTAGEN provides genome comparison and graphical sequence browsers.
It supports user-specific adjustments due to its open-source nature.

Related Experiment Videos

The system has been used to annotate the Sulfolobus acidocaldarius genome, plasmids, and viruses.

Conclusions:

MUTAGEN is a versatile and accessible prokaryotic annotation system.
Its open-source model and web interface enhance collaborative genome research.