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Published on: September 30, 2021
[Myocardial infarction in a patient with hemophilia A--a case report]
Dorota Wójcik1, Jerzy Rekosz, Jacek Woźniak
1Oddział Kardiologiczny Wojewódzkiej Stacji Pogotowia Ratunkowego, Warszawa, Poland.
Insights
A man with hemophilia A experienced myocardial infarction. Successful angioplasty of the left anterior descending artery was performed after factor VIII administration.
Area of Science:
- Cardiology
- Hematology
Background:
- Hemophilia A is a genetic bleeding disorder.
- Coronary artery disease can occur in patients with hemophilia.
Observation:
- A 43-year-old male with hemophilia A presented with symptoms of myocardial infarction.
- Diagnostic tests confirmed an anterior wall myocardial infarction.
Findings:
- Coronary angiography revealed severe stenosis in the left anterior descending artery and occlusion of the circumflex artery.
- Percutaneous coronary intervention (PCI) of the LAD was successfully performed.
- Antihemophilic globulin (factor VIII) was administered prior to the procedure.
Implications:
- This case highlights the successful management of acute coronary syndrome in a patient with hemophilia A.
- It underscores the importance of multidisciplinary care involving cardiology and hematology.
- The use of factor VIII replacement therapy facilitated the safe performance of coronary angioplasty.
Abstract:
A 43-year-old men with hemophilia A was admitted to CCU due to anginal pain lasting for sixteen hours. ECG revealed anterior wall myocardial infarction and elevated CK and MB-CK levels confirmed the diagnosis. Exercise test performed later was positive and the patient underwent elective coronary angiography which showed 90% stenosis of left anterior descending (LAD) and closed circumflex coronary artery. Next, angioplasty of LAD, preceded by antihemophilic globulin (factor VIII) administration, was successfully performed.
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