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Updated: Aug 29, 2026

Applying the RatWalker System for Gait Analysis in a Genetic Rat Model of Parkinson's Disease
Published on: January 18, 2021
Immediate effects of speed-dependent treadmill training on gait parameters in early Parkinson's disease
Marcus Pohl1, Günter Rockstroh, Stefan Rückriem
1Department of Neurological Rehabilitation, Klinik Bavaria, An der Wolfsschlucht 1-2, D-01731 Kreischa, Germany. marcus.pohl@klinik-bavaria.de
Objective:
To compare the immediate effects of different training interventions on gait parameters in patients with early Parkinson's disease (PD).
Design:
Randomized, multiple intervention crossover pilot study.
Setting:
A rehabilitation center for adult persons with neurologic disorders.
Participants:
Seventeen patients with early PD (Hoehn and Yahr stages I through III) and gait disturbances.
Intervention:
Patients were randomly assigned to varying sequences of the following interventions over 4 consecutive days: structured speed-dependent treadmill training (STT), limited progressive treadmill training (LTT), conventional gait training (CGT), and a control intervention.
Main Outcome Measures:
Basic gait parameters (overground walking speed and stride length at self-adapted speeds) and parameters of gait analysis based on vertical ground reaction forces.
Results:
STT and LTT improved all basic gait parameters and the double stance duration compared with preintervention values (P<.05). No changes were found after CGT and the control intervention (P<.05). Significantly higher gains were observed in all basic gait parameters after STT and LTT when compared with CGT and the control intervention (P<.05). Additionally, a greater reduction of double stance duration was found after STT than after the control intervention (P<.001). No significant differences in gains were observed between STT and LTT, or between CGT and the control intervention, in all gait parameters.
Conclusion:
The main disturbances of gait in PD, namely, speed and stride length, can be improved through a single intervention of STT or LTT, but not through CGT and the control intervention.

