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Eosinophilic gastroenteritis: clinical experience with 15 patients
Ming-Jen Chen1, Cheng-Hsin Chu, Shee-Chan Lin
1Division of Gastroenterology, Department of Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan, China.
World Journal of Gastroenterology
|December 12, 2003
Summary
Eosinophilic gastroenteritis is a rare gastrointestinal disorder. Corticosteroids are effective for short-term symptom relief, but relapses are common, sometimes requiring long-term low-dose steroid treatment.
Area of Science:
- Gastroenterology
- Internal Medicine
- Allergy and Immunology
Background:
- Eosinophilic gastroenteritis (EG) is a rare condition.
- Its etiology remains unclear.
- Characterized by eosinophilic infiltration of the gastrointestinal tract.
Purpose of the Study:
- To evaluate the clinical features of eosinophilic gastroenteritis.
- To examine the diagnosis, treatment, and long-term outcomes of EG.
- To provide insights into managing this rare gastrointestinal disorder.
Main Methods:
- Retrospective review of 15 patients diagnosed with EG from 1984-2002.
- Diagnosis confirmed by histologic evaluation or radiologic imaging with eosinophilic ascites.
- Analysis of clinical presentation, treatment, and follow-up data.
Main Results:
- All patients presented with gastrointestinal symptoms, most commonly abdominal pain and diarrhea.
- 80% had hypereosinophilia.
- Corticosteroids were effective for short-term symptom resolution, but 33% of followed patients experienced relapses, with some requiring long-term low-dose steroids.
Conclusions:
- Eosinophilic gastroenteritis is a rare, relapsing-remitting condition.
- Short courses of corticosteroids are the primary treatment.
- Long-term low-dose steroids may be necessary for managing relapsing cases.