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A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
Published on: October 5, 2015
[Esophageal tuberculosis in an immunocompetent patient]
A Gómez Cedenilla1, C Garrido Durán, A Sansó Sureda
1Servicio de Medicina Interna-Digestivo. Fundación Hospital Manacor. Palma de Mallorca. Spain.
A 68-year-old man with dysphagia and weight loss was diagnosed with esophageal tuberculosis. This rare condition, caused by Mycobacterium tuberculosis, should be considered in patients with pulmonary tuberculosis.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Pulmonology
Background:
- Esophageal symptoms like dysphagia and weight loss can mimic malignancy.
- Tuberculosis (TB) is a significant global infectious disease.
- Disseminated TB can affect various organs, including the esophagus.
Observation:
- A 68-year-old male presented with three months of dysphagia and weight loss.
- Esophageal transit imaging revealed severe stenosis, initially suspected to be neoplasia.
- A granulomatous inflammatory lesion was identified upon further investigation.
Findings:
- Microbial cultures of the esophageal lesion confirmed Mycobacterium tuberculosis infection.
- Chest X-ray revealed concurrent pulmonary tuberculosis.
- The esophageal stenosis was attributed to granulomatous inflammation caused by TB.
Implications:
- Esophageal tuberculosis is an uncommon manifestation of Mycobacterium tuberculosis.
- Clinicians should consider esophageal TB in patients presenting with dysphagia and known pulmonary TB.
- Early diagnosis and appropriate anti-TB treatment are crucial for managing esophageal involvement.
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