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Intussusception and the great smog of London, December 1952
1dorothyblack@suffolkonline.net
Insights
The Great Smog of London in 1952 coincided with a rise in childhood intussusception cases. This suggests environmental pollutants may facilitate viral entry, increasing the risk of this serious intestinal condition.
Area of Science:
- Pediatric Gastroenterology
- Environmental Health
- Epidemiology
Background:
- Intussusception is a significant cause of intestinal obstruction in infants and young children.
- The Great Smog of London in 1952 was a severe air pollution event with widespread public health consequences.
Observation:
- A notable increase in intussusception cases was observed in East London hospitals during 1952.
- A distinct clustering of these cases occurred immediately before, during, and after the period of the Great Smog.
Findings:
- The total incidence of intussusception in 1952 significantly surpassed that of surrounding years.
- The temporal association suggests a potential link between the smog event and the observed rise in intussusception.
Implications:
- The findings suggest that environmental irritants, like those in smog, may compromise the intestinal barrier, potentially facilitating viral infections leading to intussusception.
- This highlights the need for further research into the environmental triggers of pediatric intussusception and the impact of air quality on child health.
Aim:
To discuss the possible significance of the increased incidence of intussusception in children in relation to the "Great Smog" of London in December 1952.
Methods:
Cases of intussusception were recorded in two hospitals in East London for the years 1951, 1952, 1953, and 1954. For 1952 the actual dates of admission were recorded.
Results:
During the year 1952 the total number of cases of intussusception greatly exceeded that in the previous and succeeding years. Immediately during and after the fog there was a clustering of cases, which only occurred during this period.
Conclusions:
The increased incidence of cases during 1952 is thought to reflect the annual variation in incidence resulting from changes in the prevalence of viruses capable of causing intussusception. The clustering of cases in relation to the fog may reflect a facilitated entry of virus through the wall of the terminal ileum due to the effect of swallowed irritants such as sulphurous acid and smoke particles.
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