Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Alternative dosing for PPI therapy: rationale and options.

David A Johnson1

  • 1Section of Gastroenterology, Eastern Virginia School of Medicine, Norfolk, Virginia, USA.

Reviews in Gastroenterological Disorders
|December 13, 2003
PubMed
Summary

Optimizing intragastric pH is key for acid suppressive therapy. Understanding proton pump inhibitor (PPI) formulations and efficacies ensures optimal patient outcomes and cost-effectiveness.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dietary Intake of Micro- and Nanoplastics: Potential Adverse GI Effects on Microbiome, Inflammation, and Neoplasia.

Microorganisms·2026
Same author

A Comprehensive Narrative Review of Potential Gastrointestinal Adverse Effects From Micro(nano) Plastic Exposure.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association·2025
Same author

Oral microbiome and inflammatory bowel disease: New understanding and call to action.

World journal of gastroenterology·2025
Same author

Whole RNA-Seq Analysis Reveals Longitudinal Proteostasis Network Responses to Photoreceptor Outer Segment Trafficking and Degradation in RPE Cells.

Cells·2025
Same author

Plastics: Here, There, and Everywhere: Implications for Gastrointestinal Health and Disease.

The American journal of gastroenterology·2025
Same author

Reducing Falls in Hospitalized Children and Adolescents with Cancer and Blood Disorders: A Quality Improvement Journey.

Pediatric quality & safety·2024

Area of Science:

  • Gastroenterology
  • Pharmacology

Background:

  • Effective control of gastric acid production is crucial for managing acid-related diseases.
  • Proton pump inhibitors (PPIs) are superior in controlling acid and promoting healing.

Purpose of the Study:

  • To emphasize the importance of understanding alternative PPI dosing formulations.
  • To guide clinicians in selecting the most appropriate PPI strategy for optimal patient outcomes and cost-effectiveness.

Main Methods:

  • Review of existing literature on PPIs and their delivery methods.
  • Analysis of efficacy data for various PPI formulations.
  • Evaluation of factors influencing patient adherence and cost-effectiveness.

Main Results:

  • Traditional PPI delivery may not suit all patients.

Related Experiment Videos

  • Alternative formulations offer varied efficacy and delivery profiles.
  • Optimizing PPI strategy requires consideration of individual patient needs.

    • Conclusions:

    • A comprehensive understanding of PPI formulations is essential for effective acid suppression.
    • Clinicians must individualize PPI therapy selection based on efficacy, patient factors, and cost.
    • Further research into novel PPI delivery systems may enhance patient care.