[Microbiologic characteristics of wound infectious process in use of ion-exchange sorbents]

In Wistar rats with modified Danilina's method a purulent wound was simulated. The animals were divided into 5 groups of treatment. In the study groups applications on the wound of ion-exchange sorbents of natural origin (ceolyt including its modification with 1% silver, multicomponent ointment with bentonit, poviargol, propolis and metronidazol) were used. In the control groups gauze bandages and polyethylenoxyde were applied. When modified ceolyt and the ointment were used, earlier reduction of general contamination lower to critical level was seen. Ceolyt modified with silver demonstrated higher antimicrobic effect on gramnegative microflora compared with ointment composition. Ceolyt and its silvered modification were studied in vitro. Zones of growth absence were detected in places of application of silvered ceolyt that testifies to antimicrobic activity of silvered composition.