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Recurrent neutrophilic eccrine hidradenitis.

E F Bernstein¹, R L Spielvogel, D L Topolsky

¹Thomas Jefferson University Department of Dermatology, Philadelphia, PA 19107-5541.

The British Journal of Dermatology

|November 1, 1992

Summary

Neutrophilic eccrine hidradenitis (NEH), a skin condition often seen in chemotherapy patients, can present with varied lesions. Prompt diagnosis and corticosteroid treatment are key, though recurrence is possible.

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Area of Science:

Dermatology
Oncology

Background:

Neutrophilic eccrine hidradenitis (NEH) is a rare neutrophilic dermatosis affecting eccrine glands.
It is frequently observed in patients undergoing chemotherapy for various malignancies.

Observation:

A single patient experienced NEH on three occasions, triggered by cytarabine and mitoxantrone chemotherapy.
The clinical presentation and lesion distribution varied significantly between episodes.

Findings:

Intravenous corticosteroid administration resulted in a rapid, positive response.
However, NEH lesions recurred following the cessation of corticosteroid treatment.

Implications:

This case highlights the diverse clinical manifestations of NEH in a single patient.

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It underscores the importance of considering NEH in chemotherapy patients with new skin lesions and the potential efficacy and limitations of corticosteroid therapy.