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Multiple glomus tumors: recognition and diagnosis.

Antonio Macedo D'Acri1, Marcia Ramos-e-Silva, Carlos Basílio-de-Oliveira

  • 1The Universidade Federal do Rio de Janeiro (UFRJ), Praça Saens Pena 45/1101, 20520-090 Rio de Janeiro, Brazil. antoniodacri@uol.com.br

Skinmed
|December 16, 2003
PubMed
Summary

Multiple glomus tumors are rare, presenting diverse clinical and epidemiological features. This case series highlights varied lesion presentations and locations, aiding in improved recognition and diagnosis of this uncommon condition.

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Area of Science:

  • Dermatology
  • Oncology
  • Pathology

Background:

  • Glomus tumors are rare benign neoplasms, typically presenting as solitary, painful lesions on the distal phalanges.
  • Multiple glomus tumors are exceptionally rare, with limited documented cases.

Observation:

  • This study analyzed six cases of multiple glomus tumors, focusing on epidemiological, clinical, therapeutic, and histopathologic aspects.
  • Patients were men aged 12-45, with congenital or early-onset tumors (3-25 years).
  • Lesions varied from 3-10 macules, nodules, or tumors, exhibiting diverse colors and locations (trunk, limbs), with minimal to no pain.

Findings:

  • Histopathologic evaluation using hematoxylin-eosin staining confirmed glomus tumor diagnosis, revealing characteristic glomus cells and vascular spaces.

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  • Treatment approaches ranged from complete excision to conservative management with periodic follow-up.

    • Implications:

    • This series expands understanding of the wide spectrum of multiple glomus tumors, aiding in better clinical recognition and diagnosis.
    • The findings underscore the importance of thorough histopathologic examination for accurate diagnosis of rare glomus tumor presentations.