Related Experiment Videos
Phenotypic features of Huntington's disease-like 2
Ruth H Walker1, Joseph Jankovic, Elizabeth O'Hearn
1Department of Neurology, Veterans Affairs Medical Center, Bronx Mount Sinai School of Medicine, New York, New York 10029, USA. ruth.walker@mssm.edu
Movement Disorders : Official Journal of the Movement Disorder Society
|December 16, 2003
Abstract:
Huntington's disease-like 2 is an autosomal dominantly inherited disorder due to an expansion of trinucleotide repeats. It resembles classic Huntington's disease in clinical phenotype, inheritance pattern, and neuropathological features. We highlight the clinical features of this disorder, including chorea, dystonia, parkinsonism, and cognitive deficits.