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Updated: Jul 13, 2026

Using Confocal Analysis of Xenopus laevis to Investigate Modulators of Wnt and Shh Morphogen Gradients
Published on: December 14, 2015
A large scale screen for genes (3rd chromosome) related to Wingless signaling pathway
Xin-da Lin1, Xin-hua Lin, Jia-an Chen
1Institute of Applied Entomology, Zhejiang University, Hangzhou 310029, China. linxinda@yahoo.com
Abstract:
A wing specific F1 genetic screen was carried out using the powerful Drosophila genetic system, combined with yeast FRT/FLP and GAL4/UAS system. Form the wing phenotypes and germline clone embryonic cuticle phenotypes observed in these mutant alleles, a number of mutant alleles of known or unknown genes were isolated. Among them, fifteen mutant alleles related to Wingless signal transduction were further isolated; the arm of these mutations located were determined, and their location in the chromosome were roughly mapped.
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