Related Experiment Video
Updated: Aug 29, 2026

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure
Published on: August 25, 2017
[The environmental risk factors for COPD--tobacco smoke, air pollution, chemicals]
1Third Department of Internal Medicine, Sapporo Medical University.
Abstract:
The identification of risk factors is an important step toward developing strategies for prevention and treatment of any disease. The risks of COPD are related to environmental exposures in combination with the genetic makeup of the individual. The principal environmental factor in COPD is well known--exposure to cigarette smoke--and it can be modified. However, although smoking is the best-studied COPD risk factor, it is not only one. Air pollution, occupational dusts and chemicals can also cause COPD when the exposures are sufficiently intense or prolonged. This is a summary of environmental risk factors for COPD.
Related Concept Videos
Chronic Obstructive Pulmonary Disease I: Introduction
Chronic Obstructive Pulmonary Disease-I: Introduction
Chronic Obstructive Pulmonary Disease
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation
COPD: Pathogenesis and Clinical Features
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
Chronic Obstructive Pulmonary Disease II: Emphysema

